The headline change is the extension of the weekday live concert broadcasts to Saturdays and Sundays, beginning in Manchester with the BBC Philharmonic and pianist Stephen Hough (playing the Piano Concerto No 1 of Brahms) and the Halle and soprano Lesley Garrett on September 28 and 29.
The current film music season on the network will be continued in a new Sound Of Cinema show on Saturdays at 4pm, presented by Matthew Sweet.
Jazz Record Requests at 5pm will now be followed by Jazz Line-Up from 6pm.
The Early Music Show will be reduced to a single Sunday outing from 2pm.
The main impact for many listeners, however, will be moving of Opera On 3 to a new Monday night slot, beginning on the last day of the month with the Royal Opera prodcution of Puccini's La Rondine with Angela Gheorghiu as Magda.
The change appears to spell the end for the BBC's commitment to broadcast the live Saturday night relays of the matinee performances from the Metropolitan Opera in New York, although live opera will still fill that slot "from time to time".
A spokeswoman said the BBC's schedule from the Met "will be very strong".
She added: "We'll be broadcasting as much as possible from the new season, some of which will be live and some of which will be delayed," she said.
500 Festival marks Flodden
Coronation 500 is a festival in the historic top of the town in Stirling, curated by professional vocal group Capella Nova to commemorate the Battle of Flodden and celebrate the coronation of James V of Scotland.
With complementary workshops and events in the Smith Art Gallery and Museum and at Stirling Castle, the programme culminates in a concert at the Church Of The Holy Rude on September 29.
The choir will be joined by Dunblane Cathedral Choir and Strathclyde University Chamber Choir, under the direction of Alan Tavener, to sing Carver's Mass for 10 voices and Tallis's 40-part motet Spem in Alium.
On September 25 the Stirling Area National Youth Choir of Scotland (NYCoS) and Stirling Schools' Choir give the premiere of Flodden 1513, a new composition by Ken Johnston, a great friend of the NYCoS network, at the same venue at 6pm.
A Lecture and Lunch series at noon from Wednesday to Friday will offer insights into early 16th century culture and society in Scotland.