Sales of general merchandising are forecast to have toiled in spite of aggressive discounting activity, including a "Mega Day" which offered 30% reductions on clothing on the Saturday before Christmas.
Although food sales are expected to have grown by 1.5% to 2% in the three months to the end of December, analysts anticipate that homeware and clothing will have fallen between 0.5% and 1.5%.
The figures are expected to heap pressure on chief executive Marc Bolland, who had pinned Marks' festive hopes on a revamped autumn/winter clothing range advertised by stars such as Helen Mirren.
So far Christmas has proved to be a mixed bag for UK retailers. Next, John Lewis and House of Fraser reported strong figures last week, while a profit warning was issued by Debenhams.
Tesco and Sainsbury's are expected to show it has been a tough Christmas for the "big four" supermarkets when they report this week. Analysts have pencilled in a 0.3% fall in like-for-like sales Sainsbury's, which would break its run of 35 quarters of growth, while sales at Tesco are forecast to have slid between 2% and 2.5% in the six weeks to January 4.
A survey by BDO found sales at mid-market retailers were down 2.2% in December compared with last year.