In a poll of businesses across the UK by British Chambers of Commerce, 90% of respondents reported the referendum has had no "substantive" impact on their business to date.
"One year before Scotland goes to the polls, our business survey shows that the Scottish independence referendum has left most businesses unfazed," said John Longworth, Director General of the British Chambers of Commerce.
"The debate has not yet had an appreciable impact on custom, employment or investment for the vast majority of UK companies."
The results of the survey may help allay fears of a possible backlash against Scotland or Scottish firms in the event that the ballot goes in favour of independence.
British Chambers of Commerce noted the 90% figure was "remarkably consistent", whether businesses were asked about orders and sales, employment intentions, or investment.
The employers organisation said of the 2006 respondents, 206 (around 10%) were from Scotland but did not provide further details.
Describing the survey as the "first major poll measuring the impact of the upcoming referendum on businesses across the United Kingdom" the chambers noted some 95% of business respondents in England, Wales, and Northern Ireland reported awareness of the referendum.
However, British Chambers noted that around two thirds of the firms that said the referendum had had no impact did little business with Scotland. Of those reporting no impact, some 68% reported that the majority of their trade was from outside Scotland.
The results provided indications the referendum has impacted on investment decisions made by some companies.
British Chambers of Commerce noted 5% of respondents said the referendum has had negative impacts. It said: "Of the small minority of UK companies surveyed reporting referendum-related impacts to date, the study shows unsurprisingly that these are more pronounced on companies' Scottish operations. This effect is more pronounced on forward investment."
Noting the numbers involved were small and within the statistical margin for error the organisation said further research is required to draw firmer conclusions.
Around 30% of respondents were unclear about the possible implications of the referendum.
British Chambers of Commerce said 14% of companies reporting no impact stated they do not have enough information on the referendum while 17% said it was too early to tell whether it would affect their business.
Mr Longworth said: "We support the long-standing calls from our colleagues in Scottish Chambers of Commerce for better information and real clarity from both the "yes" and "no" campaigns on what the referendum's outcomes could mean for business prospects in every nation and region."
Liz Cameron, Chief Executive of Scottish Chambers of Commerce, said: "As the referendum gets closer, more questions are being raised about what the potential outcomes might mean for doing business in Scotland."
She added: "Businesses have identified taxation, EU membership and currency as the three priorities for politicians as they prepare their competing prospectuses for a post-referendum Scotland."