Answering Mr Farage's challenge to condemn the actions of pro-independence protesters who barracked him inside an Edinburgh pub, Mr Salmond said: "We can frankly do without Ukip who dislike everybody and know absolutely nothing about Scotland."
He described Mr Farage as "someone who is out-with the context of normal politics".
Earlier in the day Mr Farage had likened parts of the independence campaign to fascism after being rescued by police when he was mobbed by rowdy protesters shouting "racist Nazi scum".
The UKIP leader was barracked by left-wing and anti-racism protesters who joined a press conference held in a bar on the Royal Mile in Edinburgh.
Press, protesters and UKIP members were all thrown out of The Canons' Gait pub by worried bar staff, forcing Mr Farage to run the gauntlet of more protesters on the streets outside.
He took refuge in a passing taxi but the driver refused to take the fare after the car was mobbed by protesters.