Syrian state television said forces loyal to President Bashar al Assad had taken control of the southern Salaheddine district of Aleppo, killing most of the rebels there and had entered other parts of the city in a fresh offensive.
However, a rebel spokesman denied Syrian forces were in total control of the area.
"Syrian forces are positioned on one side of Salaheddine but they haven't entered and clashes are continuing," he said.
State TV said dozens of "terrorists" were killed in the central district of Bab al Hadeed, close to the ancient citadel, and Bab al Nayrab in the south-east.
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