The woman spoke about the actor's appearance on Piers Morgan's Life Stories when she was interviewed by detectives for the first time.
She said she was a "gullible kid" who was raped on two different occasions in 1967 at the actor's then-home in Lancashire - the first time when she was a 15-year-old virgin.
Jurors at Preston Crown Court were yesterday played a video recording of the police interview she gave last March. Describing why she had decided to make a complaint after staying silent for more than 40 years, she referred to the ITV1 broadcast.
"He was talking about the number of women in his life," she said. "He was quite amused by it all. It made my skin crawl to be honest. It was just the way he laughed it all off."
Her complaint led to Mr Roache, who has played Ken Barlow since the launch of the soap, being charged last May with two counts of rape.
The publicity that followed led to four other women alleging he had sexually assaulted them.
Mr Roache, 81, of Wilmslow, Cheshire, denies the rapes and five counts of indecent assault involving the four other complainants aged 16 and under between 1965 and 1971.
The rape complainant recalled a conversation with her son, where she told somebody for the first time, after the emergence of the Jimmy Savile scandal. Asked in the police interview why she had decided to make a complaint, the alleged victim told the female officer: "It has eaten away at me. I now realise what happened to me was not an isolated incident."
The trial continues.