Professor Alastair Thompson of Dundee University, who co-wrote a new study, warned vital gaps in breast cancer research must be tackled to prevent a further 185,000 deaths in the UK over the next 27 years.
Meanwhile, a YouGov poll of 500 women in Scotland revealed 61% do not check their breasts regularly for symptoms of the disease, mainly because they had forgotten to do so.
The Dundee study said scientists must unlock the genetic changes that result in breast cancer, target breast screening to those most likely to benefit and develop tests that can predict how well patients will respond to chemo- and radiotherapy.
Organised by charity the Breast Cancer Campaign and published today in the open-access journal Breast Cancer Research, the research also recommends blood and tissue samples donated by cancer patients at different stages of the disease, as well as detailed anonymous information about each patient, should be pooled and used to study breast cancer and help develop new treatments.
Professor Thompson, who worked on the research with Professor Sue Eccles of the Institute of Cancer Research in London, said: "The impact of the Gap Analysis could be immediate as it gives us scientific rationale to change clinical practice.
"For example, currently, metastatic disease is not biopsied in order to tailor treatment, but this could change the way one in six women are treated and provide hope to women with secondary breast cancer."
It also claims that with increased investment plus scientific collaboration, individual breast cancer risk could be more precisely predicted by 2025 and by 2030, patients could have care tailored to their genetics.
The separate YouGov study revealed 92% of women in Scotland cannot name five common symptoms of the disease, despite the cancer killing about 1000 women in the country per year.
It coincides with Breast Cancer Awareness Month in October.
Breakthrough Breast cancer is offering a free Touch Look Check (TLC) guide, which lists the five common signs and symptoms of breast cancer, and a free app that reminds women to regularly check their breasts.
The symptoms include feeling a lump, a discharge from the nipple or a change in the direction of the nipple, dimpling or puckering of skin, and a rash or crusting of the skin on and around the nipple.
James Jopling, Director for Scotland at Breakthrough Breast cancer said: "It's shocking that despite being the most commonly diagnosed cancer amongst women in Scotland, half of women do not check their breasts regularly, and nearly all of them still do not know five common signs and symptoms of breast cancer off the top of their head.
"Breakthrough is working hard this Breast Cancer Awareness Month to help everyone remember to TLC - Touch, Look, Check."