Mackenzie Furniss, nine, is suffering from advanced childhood cancer and needs an experimental treatment to save her life.
One of her parents, either Kimberley or Jason will give stem cells to Mackenzie - the first time the risky procedure has ever been carried out in Scotland.
The £300,000 treatment is being pioneered by German doctor Professor Peter Lang.
After Mackenzie's parents struggled to raise funds for the treatment, the Scottish Government stepped in with £160,000 to fund the stem cell donation, which will be carried out in Glasgow. The family has also had to meet the rest of the cost and have been inundated with kind donations.
Mackenzie will then need to make six return trips to Prof Lang's clinic near Stuttgart for antibody treatment to stop her body rejecting her parents' stem cells.
Kimberley, 29, said the stem cell donation was the last chance for Mackenzie.
Both parents, who are from Sauchie, Clackmannanshire, have given blood samples which scientists at Yorkhill Hospital are analysing to establish who is the best match.
Kimberley said: "Mackenzie really just wants to get back to normal and see her friends and go and play."