• Text size      
  • Send this article to a friend
  • Print this article

Scientist questions value of animal tests

Outdated reliance on animal testing is holding back progress towards effective treatments for Alzheimer's disease, a scientist has claimed.

Neurochemist Dr Gill Langley called for a fundamental "paradigm shift" away from lab mice and monkeys to new techniques based on human biology.

Writing in the journal Drug Discovery Today, she maintained that species differences had doomed research based on animal models, such as genetically engineered mice, to failure.

Decades of animal-based drug development had not found a single treatment that reversed the disease in humans, she pointed out.

She wrote: "The five approved drugs for AD (Alzheimer's disease) can stabilise symptoms temporarily, but do not slow disease progression. Around half of patients benefit modestly, but there is an urgent need for better, disease-modifying therapies as well as preventative measures."

Dr Langley is an active campaigner for animal testing alternatives and senior adviser to the animal protection organisation Human Society International.

Contextual targeting label: 
Pets

Commenting & Moderation

We moderate all comments on HeraldScotland on either a pre-moderated or post-moderated basis.
If you're a relatively new user then your comments will be reviewed before publication and if we know you well and trust you then your comments will be subject to moderation only if other users or the moderators believe you've broken the rules

Moderation is undertaken full-time 9am-6pm on weekdays, and on a part-time basis outwith those hours. Please be patient if your posts are not approved instantly.

235090