The Air Accidents Investigation Branch (AAIB) said it was sending two staff to assist local authorities probing the disaster which in total killed 19 people.
Among the Britons who died was Darren Kelly, 45, a property developer and businessman who lived in the Isle of Whithorn in Dumfries and Galloway. He died in the crash along with his brother, Vincent, 50, from Bolton.
The Dornier twin-engine propeller plane crashed two minutes after take-off from Kathmandu's Tribhuvan international airport, with initial reports suggesting a bird strike as a cause.
However, Nepalese officials are reported to have said they believe it was a pilot error which caused it to come down.
In a statement, the AAIB said: "The AAIB is sending two investigators to assist the Nepal investigation into the recent accident near Kathmandu airport."