The man was climbing with a friend in the Raeburn's Buttress area of Ben Nevis when he fell around 12.30pm yesterday.
Two helicopters were scrambled to the scene with Lochaber Mountain Rescue Team but the man died during the rescue, Northern Constabulary said.
A force spokesman said officers were trying to establish the exact circumstances around the death and no further information on the man will be issued until his family have been informed. A report is to be sent to the Procurator Fiscal.
Raeburn's Buttress is a popular climbing area on the north face of Ben Nevis which stands at 1,344m (4,409ft).
The latest death brings the number of people killed on Scotland's mountains so far this year to ten.
Doctor Rachel Majumdar, 29; PhD student Tom Chesters, 28; Christopher Bell, 24, also a PhD student; and 25-year-old junior doctor Una Finnegan died after they were caught up in an avalanche in Glencoe on January 19.
Another avalanche in the Cairngorms a fortnight ago killed RAF Squadron leader Rimon Than, 33, Flight Lieutenant Fran Capps, 32, and 18-year-old William Currie, 18, from Penzance, Cornwall.
In the same week as the second fatal avalanche a hillwalker died during an expedition with a mountaineering club in the Cairngorms.
Graham Connell, 31, from Castleford, West Yorkshire, was found dead in the Jacob's Ladder area on Monday, following a large-scale search for him and five other people who were reported overdue.
On January 26, another climber, 22-year-old Ben St Joseph, from Essex, died after falling about 100 metres from Tower Ridge on Ben Nevis.