Cannabis, heroin and amphetamine were recovered by officers in the Forth Valley area during an intelligence-led operation yesterday.
Around 50 cannabis plants with a street value of approximately £16,000 were discovered at a property in Lothian Crescent, Bo'ness.
A 33-year-old man and 29-year-old woman will appear at Falkirk Sheriff Court today.
In Falkirk, police searched a man in Newmarket Street and recovered £400 of heroin. A search of a property in Christie Terrace, Stenhousemuir, uncovered heroin worth £3,300 and amphetamine valued at £7,700. The 40-year-old is due in court today.
A 43-year-old man will also appear at Falkirk Sheriff Court in connection with £1,000 of heroin recovered during a stop and search in Grahams Road.
Chief Inspector Mandy Paterson said: "Much of yesterday's activity was carried out as a result of vital intelligence we received from our local communities.
"This has resulted in four people now awaiting trial for drug offences and demonstrates our commitment to removing those involved in these crimes from our streets.
"Police Scotland is committed to keeping people safe and will act on any information we receive relating to ongoing criminal activity.
"If you wish to report a crime in your area then please contact us on 101 or speak with your local policing team."