The Sanctuary Scotland Housing Association block at 14 Shaftesbury Street was blasted as part of the £50million regeneration of Anderston.
Sited next to one of Britian's busiest roads, the 18-storey building was brought down on Sunday morning in less than five seconds.
Peter Martin, Sanctuary's group director of development, said: "This is a significant milestone in a project which has revitalised a thriving community in the heart of Glasgow.
"The quality of our housing has not only changed the lives of Anderston residents for the better but also created many jobs and training opportunities. Conditions remain tough in construction but Sanctuary continues to support the sector through our extensive new-build programme.
"The demolition of 14 Shaftesbury Street is not an end but another new beginning for Anderston. It allows us to create better homes to house even more local families for many decades to come."
Residents in 320 neighbouring properties were evacuated as a safety precaution.
Police brought traffic along the M8 to a rolling stopped shortly before the three-minute warning klaxon sounded.
Cars were halted, leaving the M8 at Charing Cross empty, while locals gathered to watch the blowdown.
As the building fell at 11.29am clouds of dust blew across the motorway, leaving watchers covered in dust.
Among the crowd was John Beattie, who had a top-floor flat in 14 Shaftesbury Street for 20 years.
His home offered unhindered views of the Kingston Bridge and Glasgow city centre.
Since moving to a new, lower-level Sanctuary flat last November, John said his heating bill has more than halved and he is now able to get out and about.
John, 79, said: "It was a great building when I first moved in but it's time to pull it down.
"It's progress. These blocks were put up in the 1960s for one reason only - to build homes quickly and get people into them.
"I saw a few bombs drop during the war so I'm not fazed seeing the building brought down. I miss the view but nothing else, life is better now."
To date, Sanctuary Scotland has built 176 new homes in Anderston and more than 2,000 affordable properties across Scotland as a whole.
By 2015, another 158 homes will be built on the land where the 50 metre tall tower block fell.
Thirty kilograms of explosive strategically placed over five blast floors demolished the 10,000 tonne structure.