The 42-year-old victim was at the wheel of a Mercedes SLK. It collided with a blue Peugeot 307 on the A90 near Lonmay, Aberdeenshire, at 6.10pm tonight.
Police units, ambulance crews and two fire crews from Fraserburgh were scrambled to the scene.
One man was taken by ambulance to Aberdeen Royal Infirmary, a spokeswoman for the ambulance service said.
The 51-year-old man who was driving the Peugeot is understood not to have serious injuries.