Last year, it was revealed a £10 million whisky distillery and visitor centre is planned for the banks of the Clyde near the new Hydro arena.
The venture in the historic Pump House will be the first distillery to open in the centre of the city for more than a century.
Glasgow Harbour is now hoping to get permission to build a hotel next to the new attraction.
Glasgow Harbour is a wholly-owned subsidiary of Peel Holdings, the owner of Clydeport.
The company was established in 2001 to regenerate 130 acres of derelict Clyde waterfront between the SECC and the Clyde Tunnel.
Euan Jamieson, Clydeport property director said: "We have put in an outline application for a 200 bedroom hotel at the east end of Yorkhill Quay next to the Pump House."
The company boss said he hoped the council would make a decision on the application this summer.
He added: "Once we know the principle is established, we would look to secure an operator under the Peel Hotels banner and probably start on site in 2015.
"The target will be for a hotel similar to the Hilton Garden Inn Hotel next to the Finnieston Crane."