Firefighters were called to a block of flats in Ardencraig Drive in the Castlemilk area of Glasgow at about 10.20pm on Thursday night.
Six people were rescued from the building while another woman escaped through a window. All suffered smoke inhalation.
Group manager Brian Winter said: "The firefighters led six people - three children, a woman and two men - to safety after quickly extinguishing the flames using a high-pressure water jet. A second woman had already left her flat via a window.
"All seven casualties were cared for by firefighters and paramedics at the scene before being taken by ambulance to the Victoria Infirmary. Specialist fire investigation officers attended and are liaising with the police."