The annual Berlin International Film Festival opened with a trip back to pre-Second World War Europe, as Anderson presented his new movie, which also stars Willem Dafoe.
Set in the 1920s, it is one of 20 films contending for the prestigious festival's main Golden Bear awards, and also stars Ralph Fiennes, Edward Norton and Bill Murray.
The Grand Budapest Hotel will also open the upcoming Glasgow Film Festival, and will be screened at the Glasgow Film Theatre on February 20.
As the Berlin film festival opens, with four Scottish-funded films in its programmes, a new version of Shakespeare's 'Scottish play', has begun shooting in Scotland and England.
Macbeth, directed by Justin Kurzel, stars the lauded actor Michael Fassbender in the title role, with Oscar winner Marion Cotillard as Lady Macbeth.
Creative Scotland, the national arts funding body, has given the movie £200,000 as well as location recce support.
It will shoot in Scotland for about eight days but it is not yet known where the work will take place.
The film, being made by Studiocanal and Film4, also stars Paddy Considine, David Thewlis, Sean Harris and Elizabeth Debicki.
Unlike modern re-tellings of the tale, the new version is set in "war torn 11th century Scotland".
A statement from StudioCanal said the film would be "a thrilling interpretation of the dramatic realities of the times and a truthful reimagining of what wartime must have really been like for one of Shakespeare's most famous and compelling characters".
The film is being produced by The King's Speech and Shame producers, See Saw.
Last year Tessa Ross, head of Film4, called Kurzel, who directed Snowtown - a low budget horror film - "an exceptional director".
She said she was "very excited" at the "prospect of his visceral and urgent work" along with the "extraordinary" cast.
Fassbender, 36, has become one of the film industry's biggest stars and is in the running for an Oscar for his role in the acclaimed drama 12 Years a Slave.