Gordon Brown, 42, who appeared with Ryan Gosling in Only God Forgives, set up the Eilidh Brown Memorial Trust in 2010, in honour of his 15-year-old daughter who died from rare germ cell cancer.
The trust is aiming to raise at least £250,000 to build a respite home where other families affected by cancer can enjoy a holiday in the countryside.
They have now been granted planning permission by Stirling Council to erect the building in the countryside by Thornhill.
The Trust has so far raised more than £215,000 towards their target, and building could begin as soon as next summer.
Mr Brown, from Stirling, urged people to continue to raise funds for the home, which will help families from all over the UK.
He said: "We are so proud of everybody that has helped to get us this far and for believing in us.
"We can't wait to see the bricks and mortar transform this in to an amazing place."
Mr Brown and wife Nicole, 39, were inspired after they took Eilidh to Callum's Cabin in Rothesay, on the Isle of Bute.
To offer support to the Eilidh Brown Trust,go to www.eilidhbrown.co.uk
Meanwhile, a schoolgirl who is receiving a cancer treatment never before attempted in Scotland has made it home in time for Christmas.
Mackenzie Furniss, nine, from Sauchie, Clackmannanshire, received cash from the Scottish Government to help fund an experimental stem cell treatment and has been a patient at Royal Hospital for Sick Children in Yorkhill since October.