The statistics, published today by National Records of Scotland and ISD Scotland, cover the period of the Scottish Government's Choose Life suicide prevention strategy, which ran from 2002 to 2013.
There were 795 suicides registered in Scotland in 2013 - a 19% reduction since 2002, and close to the target of a 20% reduction.
Health Minister Michael Matheson said: "Any suicide is a tragedy which has a devastating impact on family and friends left behind, so it is very encouraging to see such a significant reduction in the suicide rate.
"A 19% reduction over a decade is testament to the dedication of many people, across the NHS and beyond, who work tirelessly to help people who might be at risk of taking their lives.
"At the end of last year I launched our new Suicide Prevention Strategy for 2013-16. This strategy sets out a range of commitments designed to continue this downward trend, and to further increase our understanding of suicide."
Alana Atkinson, lead for the National Programme for Suicide Prevention at NHS Health Scotland, said: "NHS Health Scotland has led the national programme for suicide prevention on behalf of the Scottish Government since 2008.
"Choose Life was a ground-breaking strategy and action plan that brought individuals and organisations together from across Scotland to work in partnership to prevent suicide in innovative and effective ways.
"Health Scotland will continue to contribute to the momentum we have gathered in preventing deaths by suicide over the coming years of the new strategy."