The Met Office said winds in excess of 80mph could bring down trees and cause structural damage, leading to power cuts and transport disruption in rush hour tomorrow morning.
The Environment Agency warned of surface water flooding incidents across most of England as forecasters predicted 20-40mm of rain could fall within six to nine hours.
Insurance companies have advised households to take steps to protect themselves and their property.
These include establishing an evacuation plan, ensuring gutters are clear so water can drain effectively and placing valuable items upstairs to limit flood damage.
The storm will develop over the Atlantic and is expected to hit the south-west of Britain before moving north-eastwards. It has been named the St Jude Storm after the patron saint of lost causes, whose feast day is on Monday. The Met Office described the storm as not one "you would see every year".