The Scottish SPCA took in 15 snakes in June and July respectively and 24 in August, all of which are suspected to have escaped from their homes.
Some of the most unusual discoveries include a California king snake found behind a washing machine and a rat snake which wrapped itself around a lamppost.
The charity is urging owners to do all they can to prevent their pets escaping.
Chief Inspector Fiona Henderson said: "We're regularly called to rescue stray snakes but so many in such a short space of time is highly unusual and rather worrying.
"Snakes are excellent escape artists so it's important owners ensure their vivariums are completely secure. If a vivarium doesn't already have a lock on it, we'd recommend having one fitted.
"We're not sure why there have been so many snakes found on the loose recently, although the warm weather may be a factor. Although this won't cause them to try and escape, it does mean they are more likely to remain outside if they do and there's a better chance of them being spotted.
Ms Henderson said snakes cannot survive for long outside in cool weather but added: "Thankfully, the majority of people who find stray snakes know to contact us, even if they do get a bit of a fright initially.
"Although the majority of snakes we find appear to be well cared for pets who have escaped from their homes, it's also possible some of them have been abandoned."
She emphasised owning a snake requires specialist equipment and warned the decision to buy one as a pet should not be taken lightly.