In the south-western city of Quetta, the capital of Baluchistan province, 10 people died and 37 were injured when a bomb went off near a passenger bus.
Four were in a critical condition.
The bomb was planted on a bicycle and exploded when the bus drove by, police said. Two vehicles carrying Pakistan troops had just passed the site when the bomb exploded.
In north-western Pakistan, a suicide attacker blew himself up near a police armoured vehicle about 12 miles south of the city of Peshawar, killing seven people.
Police said most of the dead were civilians but many police officers were among the 45 people left injured.
They said police had recently stepped up patrols in the area due to threats from militants from the nearby Khyber tribal region. The Pakistani army has carried out several operations in Khyber, in an effort to rid the area of militants.
No one claimed responsibility for either incident.
The Pakistani Taliban, which operates in the north-west, is currently engaged in peace talks with the government. The group has announced a ceasefire but attacks claimed by its splinter groups have continued during the negotiations.