Five adults have been found dead inside a home in Phoenix, Arizona, after a shooting in a suspected dispute about the family's business.

The names and ages of the three men and two women were not released but police said the three men were brothers and the dead women apparently were the men's mother and a spouse of one of the brothers.

Two other women and two children managed to escape the home unharmed, according to police.

One of those women told officers the shooting stemmed from a family dispute gone wrong, police spokesman Sgt Trent Crump said.

"Our dispatcher could hear shots fired in the background while that call was coming in," he said.

"A caller had been able to escape the home at that point, get out and start to give us information."

Sgt Crump said the family had origins in Morocco. During an hours-long stand-off before the bodies were found, police used a megaphone to try to communicate with the occupants of the home, addressing the family in Arabic.