The First Minister will use his keynote speech to conference to hammer home the gathering's central message: that Scotland "could and should" be an independent country.
He will argue that decisions about Scotland's future are best taken by those who live in the country, echoing the pro-independence campaign's "Yes declaration" which supporters hope one million people will sign before the referendum.
He will also highlight popular Holyrood policies and claim the Scottish Parliament has given Scots a successful "taste of independence".
Mr Salmond will tell an expected audience of 1200 supporters: "A Yes vote is not about a victory for the SNP, or even a victory for the Yes campaign, or even the huge coalition of interests and enthusiasm that supports a Yes vote.
"It will be, above all, an act of national self-confidence and self-belief.
"The case for independence is about what is best for people in Scotland wherever they come from.
"It is about who should be taking decisions about Scotland: those who live here or politicians at Westminster.
"This central question of who should be taking decisions is not an academic argument, it is a common sense argument based on our experience."
"The record of Scotland's Parliament since 1999 has demonstrated it is undeniably case."
The First Minister will claim that policies pioneered by the previous Labour-LibDem administrations - including the smoking ban and free care for the elderly - as evidence of Holyrood's successes.
He will also cite the SNP's council tax freeze, which has saves families £1200 per year compared with 1997 but which has been blamed for cuts to services.
The First Minister will tell delegates: "Let us consider what we can achieve by extending Scotland's powers over the things we don't currently control - over our welfare system, our economy, pensions and defence.
That is what a Yes vote means."
Deputy First Minister Nicola Sturgeon advanced the same argument in her speech yesterday.
In a plea to the country's undecided voters, who make up nearly a third of the electorate according to the most recent poll, Ms Sturgeon said: "Cast your mind forward and imagine how you will feel on September 19 next year.
"What outcome will make you feel more proud?
"What outcome will make you more hopeful for the future?"