Adam Matthews has become the third player to pull out of Wales' squad through injury ahead of their opening Euro 2016 qualifier against Andorra.
The 22-year-old Celtic defender follows Reading winger Hal Robson-Kanu and West Ham's James Collins in withdrawing from Chris Coleman's squad for the away game on September 9.
A statement from the Football Association of Wales said Cardiff's Declan John had been called up from the Under-21s to replace Matthews. Newcastle's Paul Dummett and Reading's Jake Taylor have already received late calls.
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