The announcement coincides with Homecoming's Whisky Month, which sees events taking place across Scotland to celebrate the national drink.
Created in 1896 in Perthshire, The Famous Grouse has been Scotland's no. 1 selling whisky for more than 30 years and sold in around 100 markets worldwide.
The agreement will see parent firm and international premium spirits company Edrington, which is headquartered in Glasgow, join the Glasgow 2014 sponsor family.
David Grevemberg, Glasgow 2014 chief executive, said: "As a company with a strong and long established presence in Scotland, we are pleased to have The Famous Grouse on board as our Official Whisky. We will be working with Edrington from now until Games time on collaborative opportunities to showcase this special product while encouraging those celebrating the Games to do so responsibly."
Ian Curle, Edrington chief executive, added: "We're excited about this perfect partnership. Edrington was born in Glasgow and over 150 years it has grown and developed to become an international business. That same spirit and dedication to excellence is at the heart of Glasgow 2014 and we're very proud to raise a toast of friendship between The Famous Grouse and the friendly games."