The swimmer is arguably the Team Scotland member under most pressure to win gold given his previous performances and his association with Glasgow 2014 as an official ambassador.
The 25-year-old begins his gold medal quest on Thursday, the first day of the competition, when he hopes to go one better than his Olympic silver medal when the 200m breaststroke final takes place at Tollcross, the pool he grew up swimming in.
And he goes into the competition content in the knowledge he has done all he can to meet those expectations.
"I'm not a robot so there have been times over the past year or so where I've had a miniature meltdown about it," he said.
"But I think that's natural and overall I think I've dealt with it well.
"I just have to keep reminding myself that no-one is ever going to put as much pressure on me as I do myself.
"I expect certain times and certain performances from myself this week and that expectation is the result of performances in the past few years and of the support we've had. That has to be a positive.
"It's the biggest race of my life, no doubt about it.
"This is our games and the Scots want to put on a show. That means medals.
"I want to take responsibility and step up on the first day and deliver a PB, and, if I do that, that's all I can do."
Jamieson's personal best stands at 2:07.43 - just 0.42 seconds outside the world record. And he is happy to admit that the world record is a target.
"Initially I was a bit nervous about putting it out there but now I think it's better to be honest about stuff like that," he said.
"It's only natural to want to improve."
Jamieson arrived in Glasgow on Sunday, following a week training in Aberdeen, to see his home city transformed by the excitement and regeneration that comes with the Games.
The Celtic fan will miss the opening ceremony at Parkhead on Wednesday night because he is racing in the 200m heats the following morning but he hopes to fully embrace the atmosphere on Thursday.
"The place looks amazing now," he said. "I was in the (athletes') village for about two hours this morning and there must have been 40 or 50 volunteers saying 'hello, how are you?' It's brilliant to have that.
"Everyone is getting involved and jumping on the buzz around the city.
"I think we have a chance to really ignite the excitement around the Commonwealth Games.
"We have the chance to write our name in the history books as hosting one of the best Commonwealth Games ever."