Coetzer will sit out the Belfast encounters, both of which Scotland must win if they are to stay in with a chance of securing automatic qualification for the 2015 World Cup.
"It's obviously disappointing to lose Kyle who is not only our captain but also one of our most experienced batsmen," said Pete Steindl, the Scotland coach. "But we have plenty depth in our squad."
Forfarshire's Craig Wallace has been called into the squad as cover while Rob Taylor, the Leicestershireleft-arm seamer who also missed the heavy defeat by Australia because of a shoulder strain, is expected to be fit for tomorrow's opener at Stormont.
Meanwhile, Matt Machan, the Sussex batsman, is relishing the prospect of a dual with his county team-mate Ed Joyce, the veteran batsman who will line up for his native Ireland, even though he has also represented England. "There's been plenty banter between us for the last few weeks," he said. "Ed and I get on really well but it's fair to say we won't be friends on Friday."
Machan, who was Scotland's top scorer against Australia with 39, believes that the 200-run defeat will have no bearing on the Irish matches. "We will have a really positive outlook going into the games," he said. "We are still a relatively new and young team and we are gelling more each time we play.
"The Irish are a decent side who have had some good results in recent seasons but the average age of their team is about 28. The average age of ours is about 23-24 and the best is definitely still to come. We are all really focused on getting to the World Cup."
Scotland will require two convincing wins to if they are to claim second place in the eight-team World Cricket League table behind Ireland.
Afghanistan would still have the chance to equal the Scots' points tally with two wins against Kenya next month, in which case the second qualifying place would be settled by net run-rate.