The Pittodrie clash is among the highlights of the post-split fixtures, which were announced by the Scottish Professional Football League on Wednesday afternoon.
Dundee United, who are also in the hunt for second spot, face a trip to Celtic Park for the May 11 finale.
The bottom-six teams finish their campaign 24 hours earlier, although one team will see their season extended for a relegation play-off, with no-one looking safe yet.
St Mirren host Hearts, Hibernian play Kilmarnock at Easter Road and Partick Thistle and Ross County meet at Firhill.
The fourth Edinburgh derby of the season has been scheduled for Easter Road on Sunday, April 27, in the second round of fixtures after the split.
Before then Hibs travel to St Mirren Park to take on the team currently occupying the play-off spot, ahead of the final round of pre-split fixtures.
But Terry Butcher's men, who are six points ahead of the Paisley side, are arguably the biggest winners of the fixture anomalies.
They have been handed an extra home game while Aberdeen lose out. The Dons were due three home games but only have two.
The SPFL draws up the original fixtures based on its pre-season prediction of who will make the top six, but the reality rarely meets expectations.
Other irregularities include Motherwell visiting fellow European hopefuls Dundee United for a third time, although the Fir Park club knew there would be an imbalance somewhere.
St Johnstone are handed a third trip to Aberdeen but manager Tommy Wright was "happy enough".
He told the club's website: "We always thought we would get two home games out of Celtic, Aberdeen and Dundee United so to have the newly crowned champions and another Tayside derby is good.
"It means two lengthy trips for the fans to Aberdeen and Inverness but they have been brilliant throughout the season and I am sure they will back us in those games."
Inverness face a third trip to Celtic Park, which will take place on Sunday, April 27 as League One champions Rangers are at home on the Saturday.
Hearts have three post-split home games to look forward to. They face the prospect of running out of cash before the end of the season if Lithuanian creditors cannot agree a deal to allow them to come out of administration.