Manager Paul Hartley has confirmed Sean Bonnett-Johnson, Declan Gallagher, Stephen Hughes and Matt Lockwood have all left Dens Park following the end of their current contracts.
Hartley has already allowed eight other players to leave the Championship title winners this summer having brought in new club captain Kevin Thomson, James McPake, Scott Bain, Philip Roberts, Greg Stewart and Simon Ferry.
Former Clyde defender Gallagher was an ever present for Hartley's side as they won their return to the Scottish Premiership by winning the second-tier title, playing in every minute of every game.
Englishman Lockwood has been allowed to leave after four years on Tayside, while Bonnett-Johnson and Hughes only signed on in January.
Hughes - who used to play for Rangers - featured just once before he was allowed to return to old club East Fife on loan, while Bonnett-Johnson failed to make it off the bench.
A Dundee spokesman said: "The club would like to thank all four players for their efforts whilst in the dark blue of Dundee and wish them all the best for the future."