The Group A leaders are aiming to strengthen their position at the top of the table ahead of Croatia. However, they will have to do it without the Manchester City defender.
The inspirational 27-year-old is expected to be out for four weeks after a scan showed he had suffered a tear in his groin during their opening Premier League win against Newcastle United.
Kompany will be hoping to be fit for Belgium's last two crucial World Cup qualifiers in Croatia and at home against Wales.
Meanwhile, Scotland will fall 18 places in next month's FIFA Rankings to 68th position and below the likes of Sierra Leone, New Zealand and Uzbekistan.
The Scots are in 50th place in the rankings table after a considerable rise in the past few months from their lowly position of 78th as recently as May this year.
However, they can expect a significant drop in the September table and Belgium will be regarded as the sixth best team in the world after a huge rise this year.
Scotland's superb win in Croatia in June propelled them up the table, but the recent loss to England has harmed them. Spain will remain the No.1 team, followed by Argentina, Germany and Colombia.