The second-placed team head to St James' Park for the early kick-off at virtually full strength. Only playmaker Philippe Coutinho is missing as he continues his recovery from a shoulder operation as full-backs Glen Johnson and Aly Cissokho and midfielder Joe Allen all return.
"We'll arrive with our strongest squad of the season against Newcastle," said Rodgers. "But I can't take anything away from how we've been. In terms of results, we've been absolutely brilliant and this is the most competitive league in the world."
Alan Pardew has challenged his Newcastle team to make a statement about the destiny of their season as they attempt to right last season's 6-0 rout by the Anfield club.
If Newcastle are to achieve their aim, they will have to find a way to shackle Liverpool front two Luis Suarez and Daniel Sturridge.
Pardew said: "They carry a threat in front of you and in behind. If you defend deep against them, they pick it up short and particularly Suarez starts running at you and causes you all sorts of problems, yet if you play a high line, then Sturridge's pace is a problem in behind.
Meanwhile, Manchester United manager David Moyes has thrown his support behind Roy Hodgson after the England manager issued an apology after making a joke involving a monkey in space at half time during the Poland match at Wembley.
"Qualifying for the World Cup is a great thing for any nation," said the Scot. "One thing is for sure - Roy is not a racist. That is 100%. Also I know I would be really disappointed if someone in the dressing room had said something that had taken place at half-time."