The Glasgow golfer produced his equal lowest ever round of an eight under par 64 to move into a three way share on eight under par in glorious conditions on the Hilversum course.
England's Graeme Storm added a 67 to move to 11-under par and three clear of his rivals as he seeks to end a five-year Tour drought since his only victory, the French Open in 2007.
Jamieson shares second with Spain's Gonzalo Fernandez-Castano (65) and Sweden's Ryder Cup star Peter Hanson (66)
Jamieson, who started at the ninth, raced to be four under par after four holes thanks to two birdies and an eagle. "It was a great start with two birdies right out of the gate and then to eagle the 12th or my fourth hole, and to be four under par after four, was a very hot start," he said.
"It's a start we all dream of walking onto the first tee but for it to happen was fantastic. But it's just great to shoot six under par on any day but on a golf course like this, where it's very tight off the tee, is doubly rewarding."
Jamieson had just 24 putts in his round and six fewer than day one.
He has now contested 56 events since joining the Tour and while still looking for a first win he warmed to the idea of being the third straight Scot after Paul Lawrie and Richie Ramsay to win on the Tour.
"That would be a great result to be the third straight Scottish winner but to win after Richie won last week in Switzerland would be really good," added Jamieson.
Bridge of Allan's Craig Lee continued to boost hopes of cementing his Tour card adding a 70 to remain at four under par.
Lee is currently lying 109th on the Race to Dubai and just six spots inside the 115 cut-off mark.