The European 800 metres silver medallist has been called into the Great Britain team for the season opener at the Emirates Arena.
Sharp returns tomorrow from Kenya after spending three weeks at UK Athletics endurance camp in Iten, alongside her fellow-Scot Eilish McColgan.
The GB squad for the five-team event will be captained by Robbie Grabarz, the Olympic high jump bronze medallist, with Dwain Chambers included over 60m and Charlie Grice earning a senior debut in the 1500m. Scotland's two Paralympic medallists, Libby Clegg and Stef Reid, will contest the 100m and long jump respectively.
"It's a great way to start the indoor season and I'm really excited about seeing British athletes competing on the track again after the winter break," said Peter Eriksson, the new UKA head coach.
"After such a successful 2012, it's really important that we keep the momentum going as we head for the World Championships in Moscow this summer. The international format in Glasgow means that we're able to come together as a team and continue to progress."
The high jumper Allan Smith has become the third Scottish athlete to earn a place in the Commonwealth squad for the Glasgow meeting.
The 20-year-old, who set a native record of 2.22m last week, will take on Grabarz but says he will not be intimidated by the challenge.
"It will be the biggest event I have been involved in: my first senior international," Smith said. "You are talking about people I have been used to watching compete on the television – some of them at the Olympics but you can't be an athlete and just watch on the telly. At some point, you have to get it into your mind that you are competing with these people and that's one aspect I've been working on with my coach."
Meanwhile, Mara Yamauchi, the two-time Olympic marathon runner, has announced her retirement at the age of 39. Yamauchi was sixth at the Beijing Games of 2008 while finishing runner-up in the 2009 London Marathon.