Sean Lineen's side lost to Italy a fortnight ago and are still looking for their first win of this year's Six Nations, against a France team who have won all three of their games so far and head the championship table.
In the backs, Damien Hoyland moves from wing to full-back, Ruairidh Young swaps the No.15 shirt for a start at centre in place of Richard Taylor who is unavailable for this game, and Sam Pequeur moves from the bench to wing.
In the forward pack, James Malcolm and D'arcy Rae come off the bench to start at hooker and prop respectively, Lewis Carmichael moves from blindside flanker to lock, with Tommy Spinks, the captain, taking the No.6 jersey. Loughborough University's Gabriel Carroll wins a first cap at openside.
Murdo McAndrew, who began his career with Howe of Fife and now plays for Clermont Auvergne in France, retains the scrum-half position. He said: "We were really disappointed with the way things went in Italy and are determined to give 100% against the French.
"Four of my clubmates are in the France squad so I know what we'll be up against but our training has been going well this week, there are good vibes around the camp and we're determined to put things right with a win to break their run."
Lineen, the head coach, added: "The players are keen to take on to the pitch what they have learned over the last few weeks. The French will provide a massive challenge for all of us but who better to bounce back against."