The Scottish Rugby Union has announced it has sold all 67,144 tickets for the match against the Welsh a week on Saturday with fans set to flock to Murrayfield in the hope of seeing a third consecutive win from the Dark Blues.
The Scots have already triumphed over Italy and Ireland and another win against Wales would keep them in contention for the Six Nations crown.
The crowd at the match against Wales on Saturday, March 9, will bring the cumulative Murrayfield attendance for international matches this season to more than 300,000.
Scottish Rugby's Director of Commercial Operations, Communications and Public Affairs, Dominic McKay, said: "As Kelly Brown said after Sunday's match against Ireland, a huge thank you to supporters for their backing of the national team and the game of rugby in our country.
"The atmosphere on Sunday was phenomenal, even for seasoned Murrayfield spectators, and what's especially pleasing for us is the number of young people, families and women who we are attracting to the stadium and who want to be with the Scotland team and create a truly inspiring occasion.
"We're striving to make a visit to Murrayfield on a Scotland match day the greatest rugby day out so we've enhanced a lot of the activities around the ground.
"We will continue to work with our supporters to further improve their experience when they come to Murrayfield and thank them for their feedback on the improvements we've made so far.
"We do occasionally receive return tickets as people find that their plans change so if you're still looking to attend the Scotland v Wales match keep an eye on our website as any return tickets will be released for sale there."
Meanwhile, Scotland international Richie Vernon will rejoin Glasgow next season after a spell with Sale.
Glasgow today announced the back-row forward had signed a three-year contract, subject to a medical, to return to the club where he played between 2007 and 2011.
The 25-year-old, who has 20 international caps, has scored 10 tries in 44 appearances for Aviva Premiership strugglers Sale.
Dundee-born Vernon said: "I have learnt a lot from my time at Sale over the last couple of seasons but this is an excellent opportunity for me to return home and play my rugby in Scotland.
"Of course it helps that I know a lot of the guys in the squad already, but I've been watching their progress this season and it's a very exciting time to be getting involved with the club."
The signing is a further boost for Warriors head coach Gregor Townsend, whose side moved three points off the top of the RaboDirect Pro12 on Friday night with victory over leaders Ulster.
Townsend said: "Richie is a great signing for the club and has a game that will fit very well with the style of rugby we're developing here at the Warriors. "He has the ability to play in all three back-row positions and is highly motivated to become a better player.
"He will provide another option amongst some very talented back-row players, each of whom know they have to keep working hard to earn their place in the side.
"He has a lot of international experience and has played at a high standard over the last couple of years in the Premiership, so we're very pleased he will be joining up with us in the summer."