Eli Walker will make his Wales debut in Saturday's Millennium Stadium Test against South Africa.
The 21-year-old Ospreys wing fills the vacancy created by Alex Cuthbert, who is nursing an ankle injury, while centre Scott Williams partners his Scarlets colleague Jonathan Davies in midfield.
There is also a return for fly-half Rhys Priestland after he missed last season's entire title-winning RBS 6 Nations campaign due to an Achilles tendon injury, while Cardiff Blues lock Bradley Davies has won coach Warren Gatland's vote to form the second-row pairing with Alun-Wyn Jones in a team captained by flanker Sam Warburton. Flanker Dan Lydiate makes his first Wales appearance since the summer of 2012 after an ankle injury, with prop Gethin Jenkins winning his 99th cap.
On the bench, Gatland has found places for Perpignan back James Hook and Scarlets back-three player Liam Williams, who had been tipped by many to pip Walker and start instead of Cuthbert. Walker, one of the deadliest finishers in the RaboDirect PRO12, suffered a back injury last season which ruined his international aspirations.
Wales v South Africa, Millennium Stadium, Saturday
L Halfpenny (Cardiff Blues); G North (Northampton), J Davies (Scarlets), S Williams (Scarlets), E Walker (Ospreys); R Priestland (Scarlets), M Phillips (unattached); G Jenkins (Cardiff Blues), R Hibbard (Ospreys), A Jones (Ospreys), B Davies (Cardiff Blues), A-W Jones (Ospreys), D Lydiate (Racing Metro), S Warburton (Cardiff Blues, capt), T Faletau (Newport Gwent Dragons)
Substitutes: K Owens (Scarlets), P James (Bath), S Andrews (Cardiff Blues), L Charteris (Perpignan), J Tipuric (Ospreys), Lloyd Williams (Cardiff Blues), J Hook (Perpignan), Liam Williams (Scarlets)
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