SECOND seed Gilles Simon will tackle Sam Querrey in the quarter-finals of the Aegon Open after easing past Joao Sousa.

The French world No.13 needed only an hour and 12 minutes to beat his Portuguese opponent 6-4 6-1 in Nottingham, while 12th seed Querrey downed Pablo Cuevas 7-6 (9/7) 7-6 (7/3).

Leonardo Mayer, the fourth seed, survived a spirited examination from Czech left-hander Jiri Vesely to progress 7-6 (7/2) 7/6 (7/5) and he will now tackle Denis Istomin for a semi-final place.

The Uzbek fired down eight aces as he defeated Sergiy Stakhovsky 7-5 6-4.

Simone Bolelli emerged victorious from an all-Italian encounter with eighth seed Adrian Mannarino, who succumbed to a 3-6 6-4 6-4 loss.

Former Australian Open finalist Marcos Baghdatis awaits the Bolognese player after conquering Alexander Zverev 6-3 6-3.

Ukrainian hopeful Alexandr Dolgopolov removed seventh seed Dominic Thiem from contention by clinching a 6-3 6-3 win in only 50 minutes.

Katie Swan's Wimbledon dream, meanwhile, is over for this year after the British teenager was beaten 6-3 6-3 by two-time quarter-finalist Tamira Paszek in the second round of qualifying.

Sixteen-year-old Swan had stunned world 118 Kristina Kucova in the first round but could not make it past her Austrian opponent on Wednesday.