So far, no-one here has been able to deal with the 16-time Grand Slam champion, her quarter-final 6-0, 6-0, trashing of Spain's hapless Carla Suarez Navarro illustrating the embarrassing gulf between the pretenders trying to make inroads in the women's game and those who stand peerlessly atop the upper echelons. Li Na fared a little better in the semi-final yet was still blown away without troubling the scorers in the opening set.
Victoria Azarenka, who stands between the American and the chance to join the elite group who have won the US Open five times, will not be such an easy nut to crack. The world No 2 has the best chance of anyone to dethrone the queen of Flushing Meadows.
Defeat in last year's final was tough to take. But the Azarenka of 2013 is a different animal. Her movement, thanks to some serious physical work off the court, has enabled her to sting Williams this year.
Staying on the baseline and attempting to out-hit Williams would be suicide. Moving her around and bringing her to the net is the plan.
Twice she has emerged triumphant in 2013, the Belurusian's defeat to the 31- year-old coming on the red dirt of Rome - not her favourite surface.
Her all-action game lends itself far better to the hard courts - both her majors have come at the Australian Open - and although the overall record is 3-12 in favour of Williams, Azarenka goes into today's final with a real chance.
"I feel like I'm a better player," said Azarenka. "I'm a more complete player all around, from the groundstrokes to movement to coming in, to variety. All those little things are coming together. I'm paying a lot more attention on how to create a bigger arsenal.
"We know each other pretty well. I know her strengths; she knows my strengths. That's what it's all about, about turning points, who wants it more, who's willing to go for it more. You've got to fight. You've got to run, you've got to grind."
Azarenka is certainly tapping into to the starry-eyed kids hoping dreamily to follow in her golden footsteps. Her love of music and a new-found obsession with Motown has got the world No 2 skipping to a funky, new beat.
And her relationship with crazy-haired rapper Redfoo, a tennis lover, makes Azarenka even more appealing to the masses. She said: "He has helped me to open up and be who I am more. He knows me more than the public, for sure, because we are around each other so much. He told me: 'Just bring out what you show in front of your team and how you are around your people.' That's what I'm trying to do now."
Stopping Williams, though, will be exceedingly hard. Her stats alone make phenomenal reading. She is 66-4 this year and has reached the final in 10 of 12 events, winning eight. Since Wimbledon last year, she is 97-5 with 13 titles. Closing in on an astonishing $50 million career earnings, her thirst for more titles - and more money - remains undiminished.
Her form here has been authoritative beyond belief -she has dropped a career-low 16 games in six matches, the lowest at a major in 25 years.
These two rivals are friends off the court and there is no simmering bitterness between them. "Well, I know her game as well as she knows mine," Williams said. "She knows what I do great, what I do bad and what I can do better. I know the same thing. At this point, it's just all about just playing some tennis now."
Williams's coach Patrick Mouratoglou knows just what a threat Azarenka is. "I agree that Serena's playing good tennis, but we have to be really careful not to be overconfident, especially before playing Victoria.
"She knows that Victoria is dangerous and that she will have to play her best tennis to beat her."