Adam Johnson condemned Newcastle to a fourth successive derby defeat for the first time in their history as Sunderland snatched a dramatic last-gasp 1-0 victory at St James' Park.
David Silva struck twice as Manchester City made light of their absence of strikers to brush troubled Crystal Palace aside 3-0 at the Etihad Stadium.
Andy Carroll was on target as West Ham's fourth win in five games ensured Leicester would be bottom of the Barclays Premier League at Christmas.
Arsenal's Arsene Wenger says being a football boss is about crisis management as he prepares to face a toiling Liverpool side led by Brendan Rodgers.
Aston Villa boss Paul Lambert believes Saturday's opponents Manchester United can still win the Barclays Premier League title this season despite a poor start to the campaign.