But they're not heading for a football match at Hampden or a rugby game at Murrayfield. The latest incarnation of Anglo-Scottish rivalry is to take place in a library.
On Saturday, writers Christopher Brookmyre and Kevin Williamson will, at least metaphorically, pull on Scotland blue to take on England's Joe Dunthorne and Graham Joyce in a reading competition in Glasgow.
The Literary Death Match is one of a huge number of events being staged this week as part of Book Week Scotland.