Jack Wills chief Suzanne Harlow has left the business following its acquisition by Mike Ashley's Sports Direct earlier this month.
Ms Harlow's departure comes less than a year after she assumed the post last September, having come on board as a consultant in May 2018.
Ms Harlow was said to have made "significant improvements" to Jack Wills over the last year including new product development, improving margins and halving the underlying earnings loss.
Jack Wills was put up for sale by its former owner Bluegem Capital earlier this year.
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The process came down to a head-to-head between Mr Ashley and retail rival Philip Day, the owner of Edinburgh Woollen Mill, with Sports Direct eventually buying the business out in pre-pack administration.
AstraZeneca shareholders cheered news that the drug firm's diabetes treatment Farxiga has shown promise in treating serious heart conditions.
The British pharmaceutical firm said the drug was successful in reducing the risk of fatal heart attacks or heart disease progression in patients with a common form of heart failure, following clinical trials.
Farxiga met the main goal in the trial which tested it in addition to standard treatment in patients whose hearts cannot pump enough blood.
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The drug company hopes that the testing will see Farxiga, which is already one of its best-selling treatments, receive regulatory approval for wider use for heart patients.
Shares in the company were up 2% to 7,430p.
Online retailer MySale said it is no longer for sale after completing a strategic review.
The Australia-based retail business saw its shares dive after it confirmed plans to offer a heavily discounted share placing and plough on as an independent business.
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To support its turnaround plans, MySale said it is looking to raise £10 million through a placing of shares at 2p each.
Proceeds from the fundraising will be used to repay and restructure its existing bank facilities, as well fund operations in the short term.
The company counts UK retail tycoon Sir Philip Green among its investors, holding a 20% stake, while Sports Direct founder Mike Ashley sold a stake in the company earlier this year.
Shares in MySale were down 38.9% to 2.9p.
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