Targets to eliminate pain after surgery are a major cause of the opioid crisis in several countries, according to a major new report.

Published in The Lancet, the report, which is co-authored by Professor Lesley Colvin of the University of Dundee, brings together global evidence detailing the role of surgery in the opioid crisis.

The authors conclude that pain management has been a substantial contributor to the crisis due to inappropriate prescribing of opioids. Chronic post-surgical pain is a growing problem as the population ages and more operations are carried out.

It can occur after any type of surgery.

Each year, 320 million people had surgery and chronic pain occurs in 10 per cent of cases.

The use of prescription opioids worldwide more than doubled between 2001-2013 – from 3 billion to 7.3bn daily doses per year – and doctors in many countries worldwide give medication in excess of what is needed for pain control, increasing the risks of misuse.

The authors have called for interventions including specialist pain clinics, drug monitoring policies and new pain management methods, including the use of alternative pain relief medication, to curb the crisis.

“Most people are aware of the opioid epidemic in the States, where there’s been a huge increase in strong opioids prescribed for the management of chronic pain,” said Prof Colvin, Chair of Pain Medicine at Dundee University’s School of Medicine.

“One of the things we’re trying to do is find out why that’s happened. “There’s no doubt that one of the contributors has been people having surgery. “They need strong painkillers afterwards and those painkillers are sometimes not stopped when they should be.”

Prof Colvin said a key aim was reducing the incidence of opioid misuse.

“People carry on, sometimes with chronic pain, but they carry on with bigger doses of opioids so they end up with the problems of the side effects, misuse problems, tolerance and opioid-induced hyperalgesia,” she added.

“Better understanding of the effects of opioids at neurobiological, clinical, and societal levels is required to improve future patient care. There are research gaps that must be addressed to improve the current opioid situation. Firstly, we must better understand opioid tolerance and opioid-induced hyperalgesia to develop pain relief treatments that work in these conditions.

“We also need large populationbased studies to help better understand the link between opioid use during surgery and chronic pain.”