Nicola Sturgeon has revealed she is starting to worry Prime Minister Boris Johnson is “actually now almost planning for” a no-deal Brexit.

Scotland’s First Minister told CNN’s Christiane Amanpour she thought the chances of a deal happening before the end of the Brexit transition period was now “almost vanishingly small”.

Mr Johnson warned there is a “strong possibility” the UK will fail to broker a trade agreement with the EU and on Thursday night told the nation to prepare for no-deal.

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However he also insisted negotiators would “go the extra mile” in trying to get a treaty in time for December 31.

Ms Sturgeon told CNN: “I think the chances of a deal now are almost vanishingly small. They’re not non-existent, and I remain hopeful I guess, because no-deal would be catastrophic.

“But I’m starting to worry not just that no-deal is now the overwhelming likelihood, but that Boris Johnson is actually now almost planning for that.

“Exactly a year ago right now, the UK general election took place, and he fought that election to be elected as prime minister, basically saying that his deal with the European Union was off and ready.

“He later said that no-deal would be a failure of statecraft, and it was a million-to-one chance against that happening.

“Now, today, he’s saying it is very highly probable.

“It seems to me that all of that is because Boris Johnson is failing to grasp or accept that responsible, independent countries in the modern world have to collaborate and work with others, and at times pool sovereignty for the greater good, for the greater well-being and prosperity of their populations.

“And, you know, I think he’s about to take the UK down a very, very damaging road, and for Scotland that is made all the worse, because we didn’t vote for it.”

READ MORE: Brexit makes independence more likely, say majority of Scots

It comes after Ms Sturgeon told the Scottish Parliament she is “deeply and increasingly” concerned about the lack of clarity on arrangements after the Brexit transition period ends.

She said she could not give an “absolute assurance” that a no-deal Brexit will not have an impact on the health service when concerns were raised by Scottish Greens co-leader Patrick Harvie about potential shortages of drugs and PPE.

The SNP leader was also asked about the case for Scottish independence – with numerous polls showing a majority voting Yes in the event of a second referendum – and the “bluster” of Mr Johnson, who “obviously pushes back on any SNP intervention in Parliament”.

The First Minister told Ms Amanpour: “Most things with Boris Johnson are bluster, to be perfectly frank about it, but maybe I’m biased in that regard.

“But there is a theory in Scotland of course, that every time Boris Johnson speaks about Scotland support for independence rises, so maybe I should encourage him to do more of it.

“Any country being independent brings challenges as well as opportunities. I take nothing for granted if there is, as I intend that there will be a referendum to allow people in Scotland to choose independence.

“I and those arguing for it have to persuade the majority to choose that option, and we have to do that in an open and frank way recognising the challenges as well as the massive opportunities.

“And in actual fact, do it in a way that is the polar opposite of how Boris Johnson and his colleagues argued the case for Brexit, which was to give nobody any detail and to deny all of the challenges, which is why, three-and-a-half years later, he faces the prospect of crashing out at the end of the transition period with no-deal, because he never levelled with people about the realities of Brexit and the trade-offs and the issues that had to be resolved along the way.”

Speaking of Scotland's current position within the coronavirus pandemic, the First Minister cautiously outlined her country’s progress.

“At the moment, although the second wave is still very much with us, we have a situation in Scotland where case numbers are starting to decline again. 

"The reproduction number is declining, so our focus particularly as we go into the Christmas period and deeper into the winter is to work with the population with businesses to try to make sure we all behave in a way that continues to get the virus back under control and keep it under control.”

“Our vaccination plans have started this week. 

"We've got very detailed plans in place as have the other governments of the UK, and as we get more supplies of the vaccine, the supplies have started to flow, but we don't yet know exactly what supplies we'll have over what time scale, but we are ready to go and vaccinate people as soon as those supplies are flowing. 

"We have already this week vaccinated over 5,000 people in Scotland, which our overall population is around 5 million, so while there's a long way to go, we had a very strong start to that program this weekend.”