The £26 million scheme, complete with a public green area, will be built on a 12-acre site near the entrance of Chatelherault Country Park in Hamilton, Lanarkshire.
Chatelherault, which was built in 1732, is the site of a former hunting lodge belonging to the Duke of Hamilton and the building is a popular visitor attraction.
The new 79-property development, by Robertson Homes, will be on the site of a former sawmill just south of Ferniegair Village.
It will house more than 300 people and provide up to 40 construction jobs. The company said a further 100 supply jobs would be sustained.
A spokesman said the new properties, all three, four or five-bedroom houses, had been designed to be in keeping with the surroundings.
Managing director John Murphy said: "Our plans will create a community in the next three years and breathe new life into what is a neglected site.
"We know attention to detail is important and we have designed three new types of home that offer modern standards but which fit into the surrounding area.
"This development will offer families the chance to live in a quiet semi-rural area with great views of the local countryside, easy access into the country park, and within walking distance of Chatelherault rail station."
The company said the public green would act as a "focal point" for residents. Improved access will also be created for the nearby Hamilton and District Golf Course.
Planning permission for the project, which is due to begin early next year, has been granted by South Lanarkshire Council.
Robertson said it had been working on the development for the past eight years and had carried out an extensive consultation process before getting the go-ahead for the project.
Construction is expected to begin early next year with the first houses scheduled to become available in October next year.