Organisers said they are "pulling out all the stops" as they unveiled this year's programme, which features a record 60 UK premieres.
The festival will open with the UK premiere of director Wes Anderson's The Grand Budapest Hotel, starring Ralph Fiennes, Tilda Swinton, Jude Law and Bill Murray.
The closing film is the Scottish premiere of Jonathan Glazer's Under the Skin, an adaptation of Scottish-based writer Michel Faber's novel which stars Scarlett Johansson and was partly filmed in Glasgow.
The programme features pop-up cinema events in some of the city's best-loved venues as well as collaborations between film and music, visual art, comic books and computer gaming.
Highlights include a fancy dress screening of 1974 classic Young Frankenstein at Kelvingrove Art Gallery and Museum; a "mystery cinematic descent" beneath Glasgow Central Station and a collaboration between Scottish indie band Admiral Fallow and emerging filmmakers.
Industrial warehouses in north Glasgow will be transformed for what organisers describe as a "total cinema" screening of science fiction film Tron, while Wes Anderson's The Life Aquatic with Steve Zissou, and John Carpenter's horror The Fog, will be shown in the hold of the tall ship Glenlee.
A Street Food Cinema series will combine eating with screenings of classic films such as When Harry Met Sally, Goodfellas, Rataouille and Withnail & I.
Festival co-director Allan Hunter said it had grown "almost beyond recognition" in the past decade.
He said: "Everyone is a VIP here, and in our tenth year we're pulling out all the stops, trying to create the best possible experiences for our audiences, and involving as much of the city as we can.
"2014 is set to be a thrilling year for Scotland with the Commonwealth Games, Ryder Cup and Homecoming attracting visitors from all over the world.
"Glasgow is at the heart of these celebrations and we are proud to offer our special anniversary programme as part of what promises to be an amazing period in the life of the city."
Gordon Matheson, leader of Glasgow City Council, said: "As host city for the Glasgow 2014 Commonwealth Games, we're now firmly in the global spotlight and the calibre of this year's festival programme is a strong reflection of this - it's eclectic, innovative and packed with talent from across the Commonwealth and beyond; reinforcing Glasgow's enviable status as a cinema city and must-visit destination.
"This year I am incredibly excited about the pop-up cinema strand, which presents a unique opportunity for citizens and visitors to enjoy a 'total cinema experience' in some of Glasgow's most dramatic and well-loved venues, including a special event at Kelvingrove Art Gallery and Museum."
Culture Secretary Fiona Hyslop said: "2014 is a big year for the Scotland and Glasgow Film Festival's tenth programme reflects the size and scale of what is to come this year.
"What is impressive is that the festival continues to grow, while retaining the welcoming atmosphere and engaging programme strands which made the first edition in 2005 so successful."
The festival runs from February 20 to March 2 and tickets go on sale on Friday.