A patient at North Manchester General Hospital is being tested for Ebola.
Public Health England (PHE) said testing was being done as a precaution.
It said in a statement it had received a sample for Ebola testing relating to a patient presently at North Manchester General Hospital with a history of travel to West Africa.
The statement said: "Ebola is considered unlikely but testing is being done as a precaution, as is our usual practice in these circumstances. We are confident that all appropriate actions are being taken to protect the public's health.
"As a precaution the patient is being kept in isolation until blood test results are available.
"It is not possible for PHE to provide any details on individuals being tested prior to the test result being known."
A spokesman for The Pennine Acute Hospitals NHS Trust said: "A patient in North Manchester General Hospital is undergoing a series of tests following travel to West Africa, as a precaution one of which is for Ebola.
"Our specially trained doctors and nurses are used to treating such patients, who may have a history of travel to West Africa. The patient is currently in our specialist clinical infectious diseases unit where they are being cared for in isolation, away from other patients. Strict infection control procedures remain in place and we are confident that all appropriate actions are being taken by our staff to protect the patient, the public and our staff.
"The UK has some of the best public health protection systems in the world and the risk to the UK of Ebola still remains low. We, along with other NHS Trusts, have robust and well tested systems in place to deal with suspected Ebola cases to protect staff and the public."
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