First Glasgow is scrapping journeys between Paisley and Linwood and abandoning the M8 service between the busy Silverburn shopping centre and North Pollok on the city's south side.
The bus company, which plans to make more than 30 changes to its existing timetable from next Sunday, says the latest cuts and alterations are designed to boost customer numbers.
The N9 service between the neighbouring communities of Paisley and Linwood will be stopped and routes taken by buses 9 and 9A will be revised, meaning they will no longer run between Linwood and Paisley's West End and Gauze Street.
The company says the routes are not attracting enough passengers.
The M8 service between Silverburn and North Pollok is also being withdrawn though First Glasgow said their 49 service is being revised to "largely replace" the axed bus.
City passengers face a cut to number 42 which runs between Partick Bus Station and Garscadden via Whiteinch and Scotstoun.
Some shoppers are on track for a better service.
The simpliCITY 3 runs twice an hour between Drumchapel and Govan via Partick, city centre and Silverburn.
But a new 20-minute service is being introduced on a Sunday, "during shopping hours," although buses will travel via Barrhead Road rather than Silverburn Bus Station before 9.30am and after 10.30pm.