David Grevemberg will take up the post of chief executive of the Commonwealth Games Federation (CGF) in November.
He will take over from Mike Hooper, who has been in the post for the past 14 years at the CGF, which is responsible for the direction and control of the Commonwealth Games.
Mr Grevemberg, 41, has been chief executive of Glasgow 2014 since September 2011, having previously been the organising committee's director of operations, and then chief operating officer.
He said: "It will be an honour and privilege to lead the Commonwealth sports movement on the next stage of its journey.
"This is a time of tremendous opportunity for the Commonwealth in which sport has an impactful role to play in empowering, inspiring and connecting nations and people in shared purpose.
"Glasgow 2014 is setting a new benchmark for Commonwealth Games and gives the movement sound foundations from which to build and grow.
"My immediate focus is on ensuring that - together with our Games partners - we do Glasgow and Scotland proud and deliver the best Games ever, creating a great global stage for Commonwealth athletes to shine and a wonderful festival of sport the Commonwealth can enjoy.
"I look forward to working with HRH Prince Imran, the executive board and the whole Commonwealth Games family - in particular Samoa and Gold Coast, hosts of the next Commonwealth Youth Games and Commonwealth Games.
"I'd also like to pay tribute to Mike Hooper for the commitment he has shown to Commonwealth sport over the past 14 years as the CGF's chief executive."
Before joining Glasgow 2014, Mr Grevemberg was the executive director of sport and international federation (IF) relations at the International Paralympic Committee.
Born in New Orleans in the US, he is a former wrestler and sports coach.
His new appointment comes after a meeting yesterday of the federation's executive board in Dubai.
Making the announcement, CGF president HRH Prince Imran said: "I am absolutely delighted to have a sports leader of David's calibre join us at this important time for the Commonwealth sports movement.
"He has an excellent track record for delivery and shows a real ambition for harnessing the power of sport within the Commonwealth.
"We look forward very much to the energy, vision and commitment he will bring to the Federation."
Lord Smith of Kelvin, chairman of the Glasgow 2014 organising committee, said: "I speak for the entire Glasgow 2014 team and our Games partners when I say we are absolutely thrilled at David's appointment.
"This is a real tribute to his leadership, his personal commitment and his passion for advancing sport throughout the Commonwealth.
"David is committed to delivering the best Commonwealth Games for Glasgow and Scotland and I know he will take on this next ambitious role with the same great enthusiasm and focus, and we wish him every success."
This year's Commonwealth Games run from July 23 to August 3 in Glasgow.
The 2018 Commonwealth Games will take place in Australia's Gold Coast