The 2008 Olympic gold medallist, who turned 30 on Saturday, became the second high-profile athlete in 48 hours to add Glasgow to their schedule, with Jamaican sprinter Yohan Blake targeting both 100m and 200m success.
However, Ohuruogu has scaled back her training this summer deliberately in an effort to prolong her career and maximise her chances of regaining her Olympic crown in 2016.
The Londoner will first attempt to repeat her Commonwealth victory eight years ago in Manchester, although she is concerned that her natural enthusiasm might not be enough at Hampden.
"I've been running for 10 years now, pushing 400 for 10 years which is incredibly hard on the body," she said. "I've been running world-class times for 10 years and at some point you have to be realistic and say we have to give the body time to rest.
"I'm trying to look to push again for another three years. Those three years are probably going to be even harder than the last lot have been."
Ohuruogu, who came third in the 200 metres in Saturday's Bupa CityGames in Manchester, can expect a stiff challenge in Glasgow from Jamaican athletes Steph McPherson and Novlene Williams but the 30-year-old's competitive instinct may yet give her a chance of finishing on the podium.
"It can kick in, but whether or not it's there is another matter," she said. "You can be as enthusiastic as you want but if you haven't done the work you've got no hope and no amount of enthusiasm is going to help you, unfortunately.
"It's about being a bit smarter training. I have full confidence I'll be fine. I don't have any doubts whatsoever, I think we know exactly what to pinpoint in training and what to take out so we're not really worried about that too much."
Elsewhere, Beth Potter now faces a Commonwealth dilemma after adding the 5000m qualifying mark - with a 15:40 run at the BMC meeting in Watford - to the 10,000m mark she achieved last weekend.